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Rutgers Stem Cell Research Center

Providing unrestricted support for human stem cell research

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Latest Publications

  • Chen, T., Wang, X., Guo, L., Wu, M., Duan, Z., Lv, J., Tai, W., Renganathan, H., Didier, R., Li, J., Sun, D., Chen, X., He, X., Fan, J., Young, W., & Ren, Y. (2014). Embryonic Stem Cells Promoting Macrophage Survival and Function are Crucial for Teratoma Development. Frontiers in immunology, 5, 275. PubMed
  • Moore, J.C., M.H. Sheldon, and R.P. Hart (2012) Biobanking in the Era of the Stem Cell: A Technical and Operational Guide, Colloquium Series on Stem Cell Biology, Morgan & Claypool Publishers, DOI: 10.4199/C00059ED1V01Y201206SCB002 : 86 pp.
  • Ricupero, C. L., Swerdel, M. R., & Hart, R. P. (2013). Epigenome analysis of pluripotent stem cells. Methods in molecular biology (Clifton, N.J.), 997, 203-16. PubMed
  • Carlson, A. L., Florek, C. A., Kim, J. J., Neubauer, T., Moore, J. C., Cohen, R. I., Kohn, J., Grumet, M., & Moghe, P. V. (2012). Microfibrous substrate geometry as a critical trigger for organization, self-renewal, and differentiation of human embryonic stem cells within synthetic 3-dimensional microenvironments. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 26, 3240-51. PubMed
  • Barminko, J., Kim, J. H., Otsuka, S., Gray, A., Schloss, R., Grumet, M., & Yarmush, M. L. (2011). Encapsulated mesenchymal stromal cells for in vivo transplantation. Biotechnology and bioengineering, 108, 2747-58. PubMed
  • Moore, J.C., K. Atze, P. Yeung, A.J. Toro-Ramos, C. Camarillo, K. Thompson, C.L. Ricupero, M. Brenneman, R.I. Cohen and R.P. Hart (2010) Efficient, high-throughput transfection of human embryonic stem cells., Stem Cell Res Ther 1: 23. Abstract | PubMed
  • Lakshmipathy, U., J. Davila and R.P. Hart (2010) miRNA in pluripotent stem cells., Regen Med 5: 545-55. Abstract | PubMed
  • Moore, J.C., S. Sadowy, M. Alikani, A.J. Toro-Ramos, M.R. Swerdel, R.P. Hart and R.I. Cohen (2010) A high-resolution molecular-based panel of assays for identification and characterization of human embryonic stem cell lines., Stem Cell Res 4: 92-106. Abstract | PubMed
  • Goff, L.A., J. Davila, M.R. Swerdel, J.C. Moore, R.I. Cohen, H. Wu, Y.E. Sun and R.P. Hart (2009) Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors., PLoS One 4: e7192. Abstract | PubMed

HGINJ Stem Cell Program

The Human Genetics Institute of New Jersey Stem Cell Program is the coordinating group for stem cell research at Rutgers University. This group runs a seminar series that is webcast throughout the university, pilot service awards to promote funding of stem cell projects, and expertise on hESC, iPSC, and MSC regulatory issues within Rutgers. It is the successor to the New Jersey Stem Cell Institute.

SCRC Facilities

Procedures requiring
non-federally funded
lab space
:
  • Derivation of new ESC lines
  • Working with non-approved lines

With the new NIH Stem Cell Guidelines now in place, there is much less of a restriction on working with NIH-approved stem cell lines in a federally-funded research laboratory. However, there are still some procedures that are not allowed in a federally-funded environment.

Since the SCRC was built without federal funds these procedures may be performed in this laboratory. Prior to planning such projects, please contact Dr. Martin Grumet, director of the SCRC. Your project will need approval from the Rutgers ESCRO committee before work may begin. Rutgers researchers should apply via the Biosafety online form and note the use of embryonic-derived cells or tissues in the appropriate form.

NIMH Stem Cell Center

The Rutgers Stem Cell Research Center has partnered with the Rutgers University Cell & DNA Repository (RUCDR) to establish the NIMH Stem Cell Center. This new service of the RUCDR will archive source cells for making iPSC, will make iPSC from cells representing mental health disorders, and distribute both types of cells to NIMH-funded researchers.